Lactate-Dehydrogenase 5 is overexpressed in non-small cell lung cancer and correlates with the expression of the transketolase-like protein 1

AIMS: As one of the five Lactate dehydrogenase (LDH) isoenzymes, LDH5 has the highest efficiency to catalyze pyruvate transformation to lactate. LDH5 overexpression in cancer cells induces an upregulated glycolytic metabolism and reduced dependence on the presence of oxygen. Here we analyzed LDH5 pr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kayser, Gian, Kassem, Ahmad, Sienel, Wulf, Schulte-Uentrop, Luzie, Mattern, Dominik, Aumann, Konrad, Stickeler, Elmar, Werner, Martin, Passlick, Bernward, Hausen, Axel zur
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861018/
https://ncbi.nlm.nih.gov/pubmed/20385008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-5-22
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