Lactate-Dehydrogenase 5 is overexpressed in non-small cell lung cancer and correlates with the expression of the transketolase-like protein 1

AIMS: As one of the five Lactate dehydrogenase (LDH) isoenzymes, LDH5 has the highest efficiency to catalyze pyruvate transformation to lactate. LDH5 overexpression in cancer cells induces an upregulated glycolytic metabolism and reduced dependence on the presence of oxygen. Here we analyzed LDH5 pr...

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Hlavní autoři: Kayser, Gian, Kassem, Ahmad, Sienel, Wulf, Schulte-Uentrop, Luzie, Mattern, Dominik, Aumann, Konrad, Stickeler, Elmar, Werner, Martin, Passlick, Bernward, Hausen, Axel zur
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861018/
https://ncbi.nlm.nih.gov/pubmed/20385008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-5-22
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