Doxorubicin in Combination with a Small TGFβ Inhibitor: A Potential Novel Therapy for Metastatic Breast Cancer in Mouse Models

BACKGROUND: Recent studies suggested that induction of epithelial-mesenchymal transition (EMT) might confer both metastatic and self-renewal properties to breast tumor cells resulting in drug resistance and tumor recurrence. TGFβ is a potent inducer of EMT and has been shown to promote tumor progres...

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Detalhes bibliográficos
Main Authors: Bandyopadhyay, Abhik, Wang, Long, Agyin, Joseph, Tang, Yuping, Lin, Shu, Yeh, I-Tien, De, Keya, Sun, Lu-Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860989/
https://ncbi.nlm.nih.gov/pubmed/20442777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010365
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