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Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice

Cleft palate is a common congenital disorder that affects up to 1 in 2,500 live human births and results in considerable morbidity to affected individuals and their families. The etiology of cleft palate is complex, with both genetic and environmental factors implicated. Mutations in the transcripti...

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Hlavní autoři: Thomason, Helen A., Zhou, Huiqing, Kouwenhoven, Evelyn N., Dotto, Gian-Paolo, Restivo, Gaia, Nguyen, Bach-Cuc, Little, Hayley, Dixon, Michael J., van Bokhoven, Hans, Dixon, Jill
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860913/
https://ncbi.nlm.nih.gov/pubmed/20424327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40266
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