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Insights into the role of DNA methylation in disease through the use of mouse models

Epigenetics was originally defined as the interaction of genes with their environment that brings the phenotype into being. It now refers to the study of heritable changes in gene expression that occur without a change in DNA sequence. To date, the best understood epigenetic mechanisms are CpG DNA m...

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Detalles Bibliográficos
Autores principales: Conerly, Melissa, Grady, William M.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Limited 2010
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860849/
https://ncbi.nlm.nih.gov/pubmed/20427558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.004812
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