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High mobility group box 1 protein induces tissue factor expression in vascular endothelial cells via activation of NF-κB and Egr-1
High-mobility group box 1 protein (HMGB1), an abundant nuclear protein, was recently established as a proinflammatory mediator of experimental sepsis. Although extracellular HMGB1 has been found in atherosclerotic plaques, its potential role in the pathogenesis of atherothrombosis remains elusive. I...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860734/ https://ncbi.nlm.nih.gov/pubmed/19652887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH08-11-0759 |
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