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Inhibition of p21-activated Kinase 6 (PAK6) Increases Radiosensitivity of Prostate Cancer Cells

BACKGROUND: p21-activated kinase 6 (PAK6) is a serine/threonine kinase belonging to the p21-activated kinase (PAK) family. We investigated the role of PAK6 in radiation-induced cell death in human prostate cancer cells. METHODS: We used a short hairpin RNA (shRNA) strategy to stably knock down PAK6...

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Detalhes bibliográficos
Main Authors: Zhang, Min, Siedow, Michael, Saia, Gregory, Chakravarti, Arnab
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860659/
https://ncbi.nlm.nih.gov/pubmed/20054820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21114
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