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Immobilization of peptides with distinct biological activities onto stem cell culture substrates using orthogonal chemistries

We have used the orthogonal carbodiimide condensation and Copper-catalyzed azide-alkyne “click” cycloaddition (CuAAC) reactions to prepare self-assembled monolayers that present distinct peptides to stem cells in a bio-inert background. The approach involved first forming mixed SAMs with three compo...

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Autores principales: Hudalla, Gregory A., Murphy, William L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860651/
https://ncbi.nlm.nih.gov/pubmed/20353153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la1008208
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