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Simultaneous Genotyping of GSTT1 and GSTM1 Null Polymorphisms by Melting Curve Analysis in Presence of SYBR Green I

Due to their ability to metabolize xenobiotics, glutathione S-transferases (GSTs) play an important role in cellular protection. GST family members μ (GSTM1) and θ (GSTT1) exhibit a common polymorphism that results in the complete deletion of the gene (null allele). Homozygous deletions, which resul...

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Detalhes bibliográficos
Main Authors: Marín, Fátima, García, Nadia, Muñoz, Xavier, Capellà, Gabriel, González, Carlos A., Agudo, Antonio, Sala, Núria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860465/
https://ncbi.nlm.nih.gov/pubmed/20203006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2010.090076
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