CALHM1 P86L polymorphism does not alter amyloid-β or tau in cerebrospinal fluid

Recently, the P86L alteration in CALHM1 (calcium homeostasis modulator-1) was reported to be associated with Alzheimer’s disease (AD). Moreover, the risk allele increased amyloid-β (Aβ) levels in conditioned media from cultured cells. Therefore, we hypothesized that CALHM1 P86L may modulate Aβ or ta...

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Autors principals: Giedraitis, Vilmantas, Glaser, Anna, Sarajärvi, Timo, Brundin, RoseMarie, Gunnarsson, Malin Degerman, Schjeide, Brit-Maren, Tanzi, Rudolph E., Helisalmi, Seppo, Pirttilä, Tuula, Kilander, Lena, Lannfelt, Lars, Soininen, Hilkka, Bertram, Lars, Ingelsson, Martin, Hiltunen, Mikko
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860374/
https://ncbi.nlm.nih.gov/pubmed/20005921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2009.12.011
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