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Synthesis of 8-Heteroaryl-2′-deoxyguanosine Derivatives

We describe the synthesis of 8-heteroaromatic-2′-deoxyguanosine analogues using Suzuki-Miyaura or Stille conditions. Unprotected and protected 8-bromo-2′-deoxyguanosine was coupled with commercially available heteroarylboronic acids or the trialkyltin derivatives of 2-pyridylbromides either with or...

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Detalhes bibliográficos
Main Authors: Hobley, Gerard, Gubala, Vladimir, Rivera-Sánchez, María del C., Rivera, José M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860324/
https://ncbi.nlm.nih.gov/pubmed/20428320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-2007-1077795
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