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Sulfonylurea pharmacogenomics in Type 2 diabetes: the influence of drug target and diabetes risk polymorphisms
The sulfonylureas stimulate insulin release from pancreatic β cells, and have been a cornerstone of Type 2 diabetes pharmacotherapy for over 50 years. Although sulfonylureas are effective antihyperglycemic agents, interindividual variability exists in drug response (i.e., pharmacodynamics), disposit...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860269/ https://ncbi.nlm.nih.gov/pubmed/20222815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/erc.09.154 |
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