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Iminodiacetic-phosphoramidates as metabolic prototypes for diversifying nucleic acid polymerization in vivo

Previous studies in our laboratory proved that certain functional groups are able to mimic the pyrophosphate moiety and act as leaving groups in the enzymatic polymerization of deoxyribonucleic acids by HIV-1 reverse transcriptase. When the potential leaving group possesses two carboxylic acid moiet...

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Hlavní autoři: Giraut, Anne, Song, Xiao-ping, Froeyen, Matheus, Marlière, Philippe, Herdewijn, Piet
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860114/
https://ncbi.nlm.nih.gov/pubmed/20097909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1246
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