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ERBB1 and ERBB2 have distinct functions in tumor cell invasion and intravasation

PURPOSE: The EGF receptor (ERBB1) and related family member HER2/neu (ERBB2) are often overexpressed in aggressive breast cancers and their overexpression is correlated with poor prognosis. Clinical studies using ERBB inhibitors have focused on tumor growth effects, but ERBBs can contribute to malig...

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Bibliografiske detaljer
Main Authors: Kedrin, Dmitriy, Wyckoff, Jeffrey, Boimel, Pamela J., Coniglio, Salvatore J., Hynes, Nancy E., Arteaga, Carlos L., Segall, Jeffrey E.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859965/
https://ncbi.nlm.nih.gov/pubmed/19458057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2163
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