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Neurochemical changes in Huntington R6/2 mouse striatum detected by in vivo (1)H NMR spectroscopy

The neurochemical profile of the striatum of R6/2 Huntington's disease mice was examined at different stages of pathogenesis using in vivo (1)H NMR spectroscopy at 9.4 T. Between 8 and 12 weeks, R6/2 mice exhibited distinct changes in a set of 17 quantifiable metabolites compared with littermat...

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Detalhes bibliográficos
Main Authors: Tkac, Ivan, Dubinsky, Janet M., Keene, C. Dirk, Gruetter, Rolf, Low, Walter C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859960/
https://ncbi.nlm.nih.gov/pubmed/17217418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2006.04323.x
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