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Prions of Ruminants Show Distinct Splenotropisms in an Ovine Transgenic Mouse Model

BACKGROUND: Transmissible agents involved in prion diseases differ in their capacities to target different regions of the central nervous system and lymphoid tissues, which are also host-dependent. METHODOLOGY/PRINCIPAL FINDINGS: Protease-resistant prion protein (PrP(res)) was analysed by Western bl...

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Detalhes bibliográficos
Main Authors: Baron, Thierry, Bencsik, Anna, Morignat, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859945/
https://ncbi.nlm.nih.gov/pubmed/20436680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010310
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