Initial Fitness Recovery of HIV-1 Is Associated with Quasispecies Heterogeneity and Can Occur without Modifications in the Consensus Sequence

BACKGROUND: Fitness recovery of HIV-1 “in vitro” was studied using viral clones that had their fitness decreased as a result of plaque-to-plaque passages. PRINCIPAL FINDINGS: After ten large population passages, the viral populations showed an average increase of fitness, although with wide variatio...

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Main Authors: Bordería, Antonio V., Lorenzo-Redondo, Ramon, Pernas, Maria, Casado, Concepción, Alvaro, Tamara, Domingo, Esteban, Lopez-Galindez, Cecilio
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2010
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859943/
https://ncbi.nlm.nih.gov/pubmed/20436678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010319
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