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Protein Evolution via Amino Acid and Codon Elimination

BACKGROUND: Global residue-specific amino acid mutagenesis can provide important biological insight and generate proteins with altered properties, but at the risk of protein misfolding. Further, targeted libraries are usually restricted to a handful of amino acids because there is an exponential cor...

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Detalhes bibliográficos
Main Authors: Goltermann, Lise, Larsen, Marie Sofie Yoo, Banerjee, Rajat, Joerger, Andreas C., Ibba, Michael, Bentin, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859931/
https://ncbi.nlm.nih.gov/pubmed/20436666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010104
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