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Protein Evolution via Amino Acid and Codon Elimination
BACKGROUND: Global residue-specific amino acid mutagenesis can provide important biological insight and generate proteins with altered properties, but at the risk of protein misfolding. Further, targeted libraries are usually restricted to a handful of amino acids because there is an exponential cor...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859931/ https://ncbi.nlm.nih.gov/pubmed/20436666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010104 |
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