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A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype

BACKGROUND: Our laboratory and others reported that the stimulation of specific Toll-like receptors (TLRs) affects the immune modulating responses of human multipotent mesenchymal stromal cells (hMSCs). Toll-like receptors recognize “danger” signals, and their activation leads to profound cellular a...

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Détails bibliographiques
Auteurs principaux: Waterman, Ruth S., Tomchuck, Suzanne L., Henkle, Sarah L., Betancourt, Aline M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859930/
https://ncbi.nlm.nih.gov/pubmed/20436665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010088
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