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INSULIN BIOSYNTHESIS IN THE RAT: DEMONSTRATION OF TWO PROINSULINS

Proinsulin, a single-chain precursor of insulin, has been detected in biosynthetic studies in vitro,(1-4) and in crystalline preparations of insulin from several species.(1, 5-7) It appears that proinsulin normally serves neither as a major storage nor secretory form of the hormone.(8) Its primary f...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Clark, Jeffrey L., Steiner, Donald F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1969
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC285984/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4890253/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.62.1.278
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