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Stoichiometry and architecture of active DNA replication machinery in Escherichia coli

The multiprotein replisome complex that replicates DNA, has been extensively characterized in vitro, but its composition and architecture in vivo is unknown. Using millisecond single molecule fluorescence microscopy in living cells expressing YPet derivatives of replisome components, we have examine...

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Detalhes bibliográficos
Main Authors: Reyes-Lamothe, Rodrigo, Sherratt, David J., Leake, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859602/
https://ncbi.nlm.nih.gov/pubmed/20413500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1185757
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