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An Intersubunit Interaction between S4-S5 Linker and S6 Is Responsible for the Slow Off-gating Component in Shaker K(+) Channels

Voltage-gated ion channels are controlled by the membrane potential, which is sensed by peripheral, positively charged voltage sensors. The movement of the charged residues in the voltage sensor may be detected as gating currents. In Shaker K(+) channels, the gating currents are asymmetric; although...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Batulan, Zarah, Haddad, Georges A., Blunck, Rikard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859562/
https://ncbi.nlm.nih.gov/pubmed/20202932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.097717
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