The Pax6b Homeodomain Is Dispensable for Pancreatic Endocrine Cell Differentiation in Zebrafish

Pax6 is a well conserved transcription factor that contains two DNA-binding domains, a paired domain and a homeodomain, and plays a key role in the development of eye, brain, and pancreas in vertebrates. The recent identification of the zebrafish sunrise mutant, harboring a mutation in the pax6b hom...

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Autori principali: Verbruggen, Vincianne, Ek, Olivier, Georlette, Daphné, Delporte, François, Von Berg, Virginie, Detry, Nathalie, Biemar, Frédéric, Coutinho, Pedro, Martial, Joseph A., Voz, Marianne L., Manfroid, Isabelle, Peers, Bernard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859549/
https://ncbi.nlm.nih.gov/pubmed/20177065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.108019
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