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Hypersensitivity reaction and acute immune-mediated thrombocytopenia from oxaliplatin: two case reports and a review of the literature

BACKGROUND: Oxaliplatin is a platinum compound used in the treatment of gastrointestinal malignancies, including colorectal cancer. The incidence of hypersensitivity reaction in patients receiving oxaliplatin is approximately 15%, with severe reaction (grade 3 and 4) occurring in 2% of patients. CAS...

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Detalhes bibliográficos
Main Authors: Bautista, Marnelli A, Stevens, W Tait, Chen, Chien-Shing, Curtis, Brian R, Aster, Richard H, Hsueh, Chung-Tsen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859393/
https://ncbi.nlm.nih.gov/pubmed/20346128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-3-12
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