Inhibition of HIV-1 replication by small interfering RNAs directed against Glioma Pathogenesis Related Protein (GliPR) expression

BACKGROUND: Previously, we showed that glioma pathogenesis related protein (GliPR) is induced in CEM T cells upon HIV-1 infection in vitro. To examine whether GliPR plays a role as HIV dependency factor (HDF), we tested the effect of GliPR suppression by siRNA on HIV-1 replication. RESULTS: Inductio...

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Hauptverfasser: Capalbo, Gianni, Müller-Kuller, Thea, Dietrich, Ursula, Hoelzer, Dieter, Ottmann, Oliver G, Scheuring, Urban J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859388/
https://ncbi.nlm.nih.gov/pubmed/20356381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-26
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