Associations of IL6 polymorphisms with lung function decline and COPD

BACKGROUND: Interleukin-6 (IL6) is a pleiotropic pro-inflammatory and immunomodulatory cytokine which likely plays an important role in the pathogenesis of COPD. There is a functional single nucleotide polymorphism (SNP), −174G/C, in the promoter region of IL6. We hypothesized that IL6 SNPs influenc...

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Detalhes bibliográficos
Main Authors: He, Jian-Qing, Foreman, Marilyn G., Shumansky, Karey, Zhang, Xuekui, Akhabir, Loubna, Sin, Don D, Man, S F Paul, DeMeo, Dawn L., Litonjua, Augusto A., Silverman, Edwin K., Connett, John E, Anthonisen, Nicholas R, Wise, Robert A, Paré, Peter D, Sandford, Andrew J
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859187/
https://ncbi.nlm.nih.gov/pubmed/19359268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2008.111278
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