Structural basis of HIV-1 tethering to membranes by the Bst2/tetherin ectodomain

The restriction factor Bst2/tetherin contains two membrane anchors which are employed to retain some enveloped viruses including HIV-1 tethered to the plasma membrane in the absence of virus encoded antagonists. The 2.77 Å crystal structure of the extracellular core presented here reveals a parallel...

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Main Authors: Hinz, Andreas, Miguet, Nolwenn, Natrajan, Ganesh, Usami, Yoshiko, Yamanaka, Hikaru, Renesto, Patricia, Hartlieb, Bettina, McCarthy, Andrew A., Simorre, Jean-Pierre, Gottlinger, Heinrich, Weissenhorn, Winfried
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859121/
https://ncbi.nlm.nih.gov/pubmed/20399176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.03.005
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