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Aging-related hyperinflammation in endotoxemia is mediated by the α(2A)-adrenoceptor and CD14/TLR4 pathways
AIMS: Sepsis is a major cause of morbidity and mortality in the elderly population. In prior studies, we have shown that in vivo, the inflammatory response in aged animals is exaggerated as compared to young animals and that this response likely accounts for the increased morbidity and mortality. Pa...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859120/ https://ncbi.nlm.nih.gov/pubmed/20302880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2010.03.009 |
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