Predictive Features of Severe Acquired ADAMTS13 Deficiency in Idiopathic Thrombotic Microangiopathies: The French TMA Reference Center Experience

Severe ADAMTS13 deficiency occurs in 13% to 75% of thrombotic microangiopathies (TMA). In this context, the early identification of a severe, antibody-mediated, ADAMTS13 deficiency may allow to start targeted therapies such as B-lymphocytes-depleting monoclonal antibodies. To date, assays exploring...

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Główni autorzy: Coppo, Paul, Schwarzinger, Michael, Buffet, Marc, Wynckel, Alain, Clabault, Karine, Presne, Claire, Poullin, Pascale, Malot, Sandrine, Vanhille, Philippe, Azoulay, Elie, Galicier, Lionel, Lemiale, Virginie, Mira, Jean-Paul, Ridel, Christophe, Rondeau, Eric, Pourrat, Jacques, Girault, Stéphane, Bordessoule, Dominique, Saheb, Samir, Ramakers, Michel, Hamidou, Mohamed, Vernant, Jean-Paul, Guidet, Bertrand, Wolf, Martine, Veyradier, Agnès
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2010
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859048/
https://ncbi.nlm.nih.gov/pubmed/20436664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010208
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