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Adeno-associated virus-mediated transfer of endothelial nitric oxide synthase gene reduces the vasoconstrictive response

BACKGROUND: Adeno-associated virus (AAV) has a number of attractive features for gene therapy including the ability to transduce nondividing cells and long term transgene expression. OBJECTIVE: To investigate whether the endothelial constitutive nitric oxide synthase (ecNOS) gene can be efficiently...

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Dettagli Bibliografici
Autori principali: Maeda, Yoshikazu, Ikeda, Uichi, Shimpo, Masahisa, Ishibashi, Shojiro, Takizawa, Toshihiro, Monahan, John, Ozawa, Keiya, Shimada, Kazuyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Pulsus Group Inc 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858966/
https://ncbi.nlm.nih.gov/pubmed/20428445
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