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Toll-like Receptor 4 Ligands Induce IFN-α Production By Mouse Conventional Dendritic Cells and Human Monocytes After IFN-β Priming

Exacerbation of disease in systemic lupus erythematosus (SLE) is associated with bacterial infection. In conventional dendritic cells (cDCs), the Toll-like receptor 4 (TLR4) ligand bacterial lipopolysaccharide (LPS) induces interferon (IFN)-β gene expression but does not induce IFN-α. We hypothesize...

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Bibliografische gegevens
Hoofdauteurs: Richez, Christophe, Yasuda, Kei, Watkins, Amanda A., Akira, Shizuo, Lafyatis, Robert, Van Seventer, Jean, Rifkin, Ian R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858919/
https://ncbi.nlm.nih.gov/pubmed/19124725
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