The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

BACKGROUND: TMEM18 is a hypothalamic gene that has recently been linked to obesity and BMI in genome wide association studies. However, the functional properties of TMEM18 are obscure. METHODS: The evolutionary history of TMEM18 was inferred using phylogenetic and bioinformatic methods. The gene...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Almén, Markus Sällman, Jacobsson, Josefin A, Shaik, Jafar HA, Olszewski, Pawel K, Cedernaes, Jonathan, Alsiö, Johan, Sreedharan, Smitha, Levine, Allen S, Fredriksson, Robert, Marcus, Claude, Schiöth, Helgi B
التنسيق: Artigo
اللغة:Inglês
منشور في: BioMed Central 2010
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858727/
https://ncbi.nlm.nih.gov/pubmed/20380707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-58
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