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A Differential Role for Macropinocytosis in Mediating Entry of the Two Forms of Vaccinia Virus into Dendritic Cells

Vaccinia virus (VACV) is being developed as a recombinant viral vaccine vector for several key pathogens. Dendritic cells (DCs) are specialised antigen presenting cells that are crucial for the initiation of primary immune responses; however, the mechanisms of uptake of VACV by these cells are uncle...

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Autors principals: Sandgren, Kerrie J., Wilkinson, John, Miranda-Saksena, Monica, McInerney, Gerald M., Byth-Wilson, Karen, Robinson, Phillip J., Cunningham, Anthony L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858709/
https://ncbi.nlm.nih.gov/pubmed/20421949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000866
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