Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development

The transcription factor POU5f1/OCT4 controls pluripotency in mammalian ES cells, but little is known about its functions in the early embryo. We used time-resolved transcriptome analysis of zebrafish pou5f1 MZspg mutant embryos to identify genes regulated by Pou5f1. Comparison to mammalian systems...

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Hlavní autoři: Onichtchouk, Daria, Geier, Florian, Polok, Bozena, Messerschmidt, Daniel M, Mössner, Rebecca, Wendik, Björn, Song, Sungmin, Taylor, Verdon, Timmer, Jens, Driever, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858445/
https://ncbi.nlm.nih.gov/pubmed/20212526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.9
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