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Comparison between Steroid Binding to Progesterone Membrane Receptor α (mPRα) and to Progesterone Nuclear Receptor: Correlation with Physicochemical Properties Assessed by Comparative Molecular Field Analysis and Identification of mPRα-specific Agonists

Recent results showing that the binding characteristics of 33 steroids for human membrane progesterone receptor alpha (hu-mPRα) differ from those for the nuclear progesterone receptor (nPR) suggest that hu-mPRα-specific agonists can be identified for investigating its physiological functions. The bi...

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Detalhes bibliográficos
Main Authors: Kelder, Jan, Azevedo, Rita, Pang, Yefei, de Vlieg, Jacob, Dong, Jing, Thomas, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858063/
https://ncbi.nlm.nih.gov/pubmed/20096719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2010.01.010
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