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The NH(2)-terminal region of S. pyogenes M5 protein confers protection against degradation by proteases and enhances mucosal colonization of mice
BACKGROUND: The NH(2)-terminal sequence of the M protein from group A streptococci (GAS) defines the serotype of the organism and contains epitopes that evoke bactericidal antibodies. METHODS: To identify additional roles for this region of the M protein, we constructed a mutant of M5 GAS expressing...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858045/ https://ncbi.nlm.nih.gov/pubmed/20367460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/652005 |
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