Increased metabolic vulnerability in early-onset Alzheimer’s disease is not related to amyloid burden

Patients with early age-of-onset Alzheimer’s disease show more rapid progression, more generalized cognitive deficits and greater cortical atrophy and hypometabolism compared to late-onset patients at a similar disease stage. The biological mechanisms that underlie these differences are not well und...

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Detalhes bibliográficos
Main Authors: Rabinovici, Gil D., Furst, Ansgar J., Alkalay, Adi, Racine, Caroline A., O’Neil, James P., Janabi, Mustafa, Baker, Suzanne L., Agarwal, Neha, Bonasera, Stephen J., Mormino, Elizabeth C., Weiner, Michael W., Gorno-Tempini, Maria L., Rosen, Howard J., Miller, Bruce L., Jagust, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858015/
https://ncbi.nlm.nih.gov/pubmed/20080878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awp326
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