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Detection of low-frequency pretherapy chemokine (CXC motif) receptor 4-using HIV-1 with ultra-deep pyrosequencing

OBJECTIVE: Identification of low-frequency variants is of clinical importance in the identification of preexisting drug resistance. Using ‘ultra-deep’ sequencing, we address the detection of potential resistance to the chemokine (C–C motif) receptor 5 antagonist, maraviroc, due to the pretreatment p...

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Detalhes bibliográficos
Main Authors: Archer, John, Braverman, Michael S., Taillon, Bruce E., Desany, Brian, James, Ian, Harrigan, P. Richard, Lewis, Marilyn, Robertson, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857961/
https://ncbi.nlm.nih.gov/pubmed/19424056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32832b4399
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