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Treatment With Recombinant Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Alleviates the Severity of Streptozotocin-Induced Diabetes

OBJECTIVE: To evaluate the potential therapeutic effect of recombinant human tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) treatment in a model of type 1 diabetes. RESEARCH DESIGN AND METHODS: Recombinant TRAIL was added in vitro to primary human and mouse peripheral blood mo...

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Detalhes bibliográficos
Main Authors: Zauli, Giorgio, Toffoli, Barbara, di Iasio, Maria Grazia, Celeghini, Claudio, Fabris, Bruno, Secchiero, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857907/
https://ncbi.nlm.nih.gov/pubmed/20185810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1771
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