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The efficacies of clozapine and haloperidol in refractory schizophrenia are related to DTNBP1 variation

OBJECTIVE: The prototypical atypical antipsychotic agent, clozapine, is more efficacious for refractory schizophrenia than the “typical” antipsychotics, but the mechanism underlying this enhanced efficacy is still under investigation. Since 2002, at least 22 association studies have demonstrated tha...

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Detalhes bibliográficos
Main Authors: Zuo, Lingjun, Luo, Xingguang, Krystal, John H., Cramer, Joyce, Charney, Dennis S., Gelernter, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857717/
https://ncbi.nlm.nih.gov/pubmed/19369910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32832b9cfc
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