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A Single Amino Acid Change Converts the Sugar Sensor SGLT3 into a Sugar Transporter

BACKGROUND: Sodium-glucose cotransporter proteins (SGLT) belong to the SLC5A family, characterized by the cotransport of Na(+) with solute. SGLT1 is responsible for intestinal glucose absorption. Until recently the only role described for SGLT proteins was to transport sugar with Na(+). However, hum...

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Hlavní autoři: Bianchi, Laura, Díez-Sampedro, Ana
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857651/
https://ncbi.nlm.nih.gov/pubmed/20421923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010241
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