Epididymal Hypo-Osmolality Induces Abnormal Sperm Morphology and Function in the Estrogen Receptor Alpha Knockout Mouse

Estrogen receptor-alpha (ESR1) is highly expressed in the efferent ductules of all species studied as well as in the epididymal epithelium in mice and other select species. Male mice lacking ESR1 (Esr1KO) are infertile, but transplantation studies demonstrated that Esr1KO germ cells are capable of f...

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Main Authors: Joseph, Avenel, Shur, Barry D., Ko, CheMyong, Chambon, Pierre, Hess, Rex A.
Format: Artigo
Jezik:Inglês
Izdano: Society for the Study of Reproduction, Inc. 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857636/
https://ncbi.nlm.nih.gov/pubmed/20130266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.080366
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