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The Environmental Toxicant 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Disturbs the Establishment and Maintenance of Cell Polarity in Preimplantation Rat Embryos

Maternal exposure to the environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces a variety of defects in compaction-stage embryos, including monopolar spindle formation, errors in chromosome segregation, and fragmentation resulting from aberrant cytokinesis. In this study, we inves...

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Detalhes bibliográficos
Main Authors: Hutt, Karla J., Shi, Zhanquan, Petroff, Brian K., Albertini, David F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857633/
https://ncbi.nlm.nih.gov/pubmed/20089886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.081109
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