Investigations of the Y Chromosome, Male Founder Structure and YSTR Mutation Rates in the Old Order Amish

OBJECTIVES: Using Y chromosome short tandem repeat (YSTR) genotypes, (1) evaluate the accuracy and completeness of the Lancaster County Old Order Amish (OOA) genealogical records and (2) estimate YSTR mutation rates. METHODS: Nine YSTR markers were genotyped in 739 Old Order Amish males who particip...

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Main Authors: Pollin, Toni I., McBride, Daniel J., Agarwala, Richa, Schäffer, Alejandro A., Shuldiner, Alan R., Mitchell, Braxton D., O'Connell, Jeffrey R.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2007
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857628/
https://ncbi.nlm.nih.gov/pubmed/17898540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000108941
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