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Haseman Elston Regression in Ascertained Samples: Importance of Dependent Variable and Mean Correction Factor Selection

OBJECTIVE: One of the first tools for performing linkage analysis, Haseman-Elston regression (HE), has been successfully used to identify linkages to several disease traits. A recent explosion in extensions of HE leaves one faced with the task of choosing a flavor of HE best suited for a given situa...

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Main Authors: Sinha, Ritwik, Gray-McGuire, Courtney
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857627/
https://ncbi.nlm.nih.gov/pubmed/17898537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000108938
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