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Electro-chemical coupling in the voltage-dependent phosphatase Ci-VSP

In the voltage sensing phosphatase, Ci-VSP, a voltage sensing domain (VSD) controls a lipid phosphatase domain (PD). The mechanism by which the domains are allosterically coupled is not well understood. Using an in vivo assay, we find that the inter-domain linker that connects the VSD to the PD is e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kohout, Susy C., Bell, Sarah C., Liu, Lijun, Xu, Qiang, Minor, Daniel L., Isacoff, Ehud Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857593/
https://ncbi.nlm.nih.gov/pubmed/20364128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.349
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