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Complement Activation by CpG in a Human Whole Blood Loop System: Mechanisms and Immunomodulatory Effects
Phosphorothioate oligodeoxynucleotides can activate complement, and experimental murine studies have revealed differential effects upon simultaneous TLR stimulation and complement activation compared with either event alone. We set out to investigate the immune stimulatory effects of CpG 2006 in fre...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857538/ https://ncbi.nlm.nih.gov/pubmed/19864604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902374 |
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