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Complement Activation by CpG in a Human Whole Blood Loop System: Mechanisms and Immunomodulatory Effects

Phosphorothioate oligodeoxynucleotides can activate complement, and experimental murine studies have revealed differential effects upon simultaneous TLR stimulation and complement activation compared with either event alone. We set out to investigate the immune stimulatory effects of CpG 2006 in fre...

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Détails bibliographiques
Auteurs principaux: Mangsbo, Sara M., Sanchez, Javier, Anger, Kerstin, Lambris, John D., Ekdahl, Kristina Nilsson, Loskog, Angelica S., Nilsson, Bo, Tötterman, Thomas H.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857538/
https://ncbi.nlm.nih.gov/pubmed/19864604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902374
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