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Methylation of a Single Intronic CpG Mediates Expression Silencing of the PMP24 Gene in Prostate Cancer
BACKGROUND: We previously demonstrated that a putative anti-tumor gene, peroxisomal membrane protein 4, 24 kDa (PMP24 or PXMP4), is silenced via DNA methylation of a CpG island in its 5′ flanking region (5′-CGI) in prostate cancer (PCa) cells. METHODS: To identify demethylation hypersensitive site(s...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857536/ https://ncbi.nlm.nih.gov/pubmed/20054818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21109 |
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