Can cytoplasmic nucleophosmin be detected by immunocytochemical staining of cell smears in acute myeloid leukemia?

Mutations in the C-terminal region of nucleophosmin in acute myeloid leukemia (AML) result in aberrant cytoplasmic nucleophosmin (cNPM) in leukemic blast cells which is detectable by immunocytochemistry in bone marrow trephine (BMT) biopsy sections. We tested whether cNPM is detectable by immunocyto...

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Autores principales: Mattsson, Göran, Turner, Susan H., Cordell, Jacqueline, Ferguson, David J.P., Schuh, Anna, Grimwade, Lizz F., Bench, Anthony J., Weinberg, Olga K., Marafioti, Teresa, George, Tracy I., Arber, Daniel A., Erber, Wendy N., Mason, David Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: Ferrata Storti Foundation 2010
Materias:
Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857199/
https://ncbi.nlm.nih.gov/pubmed/20015883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.011817
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