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Phosphorylation of Yeast Phosphatidylserine Synthase by Protein Kinase A: IDENTIFICATION OF SER(46) AND SER(47) AS MAJOR SITES OF PHOSPHORYLATION

The CHO1-encoded phosphatidylserine synthase from Saccharomyces cerevisiae is phosphorylated and inhibited by protein kinase A in vitro. CHO1 alleles bearing Ser(46) → Ala and/or Ser(47) → Ala mutations were constructed and expressed in a cho1Δ mutant lacking phosphatidylserine synthase. In vitro, t...

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Detalhes bibliográficos
Main Authors: Choi, Hyeon-Son, Han, Gil-Soo, Carman, George M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857031/
https://ncbi.nlm.nih.gov/pubmed/20145252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.100727
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